by train, you can stop at Lyon Part-Dieu and take the Metro, line B, towards Oullins; Stop at Metro Debourg.Then walk for 5-10 min.
You can also stop at Lyon Perrache and catch the Tram T1, direction Debourg, Stop at Ecole Normale- Walk 1 min.
In this case, you will be able to admire the architecture of the Musée des Confluences ! Both solutions are equivalent in terms of time spent.
Grand Amphithéâtre Charles Mérieux
Ecole Normale Supérieure de Lyon
Place de l'Ecole
69364 LYON cedex 07
ACCES VIA SUBWAY B - Debourg
ACCES VIA TRAM T1 - ENS Lyon